"Oh my…" Sam began, but then remembered he probably shouldn't blaspheme against Castiel's father when he was in the room. He rubbed the piece of skin off disgustedly and watched in shock as the whole of Dean's skin peeled off, leaving a bloody mess on the bed sheets.
"No, Dean you should not bleed on the hotel bed, the managers get angry when you don't have those little paper things to replace the sheets." Castiel commented, an innocent remark which was painfully out of place in the situation, but was amusing nonetheless.
"You mean money" Sam informed him. "I think we have bigger things to worry about." He pointed to the bed where a beautiful woman with long flowing mousy hair and shiny but otherwise unmarked skin lay unconscious.
Castiel cocked his head to one side in an adorable puppy fashion and pointed towards the creature. "That is Dean Winchester", he announced, as if Sam did not understand what had just happened. "How can this be? That woman's soul is the same as Dean's."
Sam's eyes were wide and he rubbed his forehead with two fingers in deep thought, tracing the lines his frown had set into it. "Yeah Cas, I think uh… I think Dean Shape shifted."
"Impossible, giving a human the abilities of a shape shifter would kill them immediately. Shape shifter DNA holds too many mutated genes, the human body would reject that amount of information and Dean would be dead." Castiel approached the unconscious form and gingerly placed two hands on her chest.
"Woah, what are you doing?" Sam demanded, hoping that there was a reason that an angel of the Lord was groping his brother's breasts. God it felt weird acknowledging that.
"I am going to have a deeper look into Dean's soul."
"Don't you think we should make him… her… decent first?"
"Decent?"
"Yeah, give her some clothes."
"Oh… is this not acceptable?"
"Not unless you want Dean to call the cops on you if he wakes up."
Castiel didn't understand since Dean had let him carry out a 'cavity search' without wearing a shirt before, but he complied with Sam's wishes and helped the younger Winchester wrap a towel around the female Dean's body. He then proceeded with his search of Dean's soul while the woman groaned in pain.
Unfortunately, they had not accounted for the fact that the pain might wake Dean up. His eyes were still blue, but were more languid and did not have the same mischievous spark. He noticed Castiel standing over him and opened his mouth to complain about the cavity search and then ask what in the hell the angel was doing back there after all the desperate times he had called for him and he had not answered. However, cruelty had other plans and as he opened his mouth, his old set of teeth tumbled out, causing him to almost literally choke on his words.
"Dean?" Sam asked as his brother's coughing slowed down.
"What in the he-" Dean stopped at the sound of his own voice, or at least the lack of his own voice. Terrified, he turned towards Sam. "Sammy… why do I sound like a woman?"
Sam's mouth opened and closed like a fish drowning in air.
"It was the shape shifter you were hunting. It injected you with its own DNA." Castiel explained, rolling the baggy sleeves of his trench coat back over his tanned arms.
Sam cleared his throat "I thought you said that would kill Dean."
"It would," Castiel noted "But Dean was not injected with full DNA. The Shape shifter somehow managed to only extract and inject into Dean the part which allows them to switch between genders."
Dean shot up as fast as lightning in the bed. "You mean I'm a chick!"
"That is not acceptable" Castiel said, pointing to the fact that Dean's towel had slipped down in his eagerness for answers.
Sam stifled a snigger "I wonder what Bobby will make of this" he asked aloud, getting out his phone and dialling before it was knocked out of his hand by Dean rushing towards him.
"No one else is going to know I'm a chick." Dean asserted before checking himself out in the mirror "Even if I am a hot chick." He shook his head like a dog shaking off water, and then rolled his eyes "Didn't anyone think to dress me? Jeez." He skulked off to his suitcase to pick out some clothes after telling both Sam and Castiel to "quit perving" while he got changed, leaving Sam and Castiel to wonder what on earth they were going to do to reverse the damage.
