Eru Illuvatar - God; the Creator; Composer and Conductor of the Great Music.

Valar

Melkor/Morgoth - Most powerful of the Valar, rebelled against Eru Illuvatar. Worker of chaos, enemy of life.

Yavanna - Mother of all life in Arda. Known to the Na'vi as Eywa. Wife of Aule.

Aule - Lord of smithcraft and industry. Husband of Yavanna.

Ulmo - Lord of the seas, father of the Tulkun - sapient, whale-like beings who dwell in Pandora's oceans.

Manwe - Chief among the Valar, representative of Eru Illuvatar.

Mandos - Judge and pronouncer of fate. Along with Manwe, is most familiar with the will of Illuvatar.

Humans

Colonel Miles Quaritch - Military commander during the first human invasion of Pandora. Caused much suffering to the Na'vi. Killed in the Battle of the Tree of Souls.

Spider (Miles) Soccoro - Estranged son of Miles Quaritch. Lives with the Na'vi.

Mick Scoresby - Sea captain and Tulkun hunter.

Grace Augustine - Scientist and ally of the Na'vi. Killed by Miles Quaritch.

Na'vi

Jake Sully - Former human soldier, pledged his loyalty to the Na'vi and became one of them after marrying Neytiri. Toruk Makto and former Olo'eyktan of the Omatacaya clan.

Neytiri - Wife of Jake Sully; hunter, warrior, and future Tsahik.

Kiri - Adopted daughter of Jake and Neytiri, biological daughter of Grace Augustine's avatar. Close friend of Spider Soccoro.

Lo'ak - Son of Jake and Neytiri.

Tsireya - Daughter of Ronal and Tonowari, leaders of the Metkayina clan. Girlfriend of Lo'ak.

Tulkun

Payakan - Spirit brother of Lo'ak. Outcast of the Tulkun, ally to the Na'vi.