Season 4

Sacred

Given information from the recently deceased Dr. Swann that he should talk to his father, Clark used the octagonal key to learn some startling news. Jor-El informed his son that he must not let any humans unite three Kryptonian stones or else the Earth was doomed.

Lana learned that her boyfriend, Jason, was working on a project for Lex. He told her that it was in Metropolis but she found out that it was actually in China. With help from Lionel, Lana learned Jason went to China and which part of the country he was traveling to. Sometime later, Clark paid her a visit and they went over what they had recently learned. They decided that their best way to learn what is truly going on is to set out for China themselves.

Once they arrived, Clark and Lana met up with a contact provided by Lionel, Professor Sen, who would assist them. The professor guided them to a temple, where Clark found a secret chamber. He went in alone to look around. Inside, Clark found a ceremonial dress along with a mask and statue that had green kryptonite eyes. That last discovery weakened Clark instantly.

Outside the chamber, Lana and Professor Sen were confronted by several armed soldiers who then killed the professor. They captured Lana and as she was taken away, they noticed the tattoo she had gotten just before her return to Smallville. As Lana was taken away, Clark continued to suffer from the effects of the kryptonite without anyone knowing where he was.

The soldiers also had Lex and Jason who were tortured mercilessly to get them to talk. Lana was brought in later to help loosen their tongues and she too was tortured. To the chagrin of the soldiers, they accidently awakened the spirit of the witch Isabelle within Lana who then fried all the men that had tormented them.

Before Isabelle could do anything else, more soldiers came in to investigate what had just happened. The group fired several shots at her, surprised to see the young woman floating in the air.

"One wave from my hand should take care of you," Isabelle told the soldiers before acting on her words.

Again, the witch used her powers to eliminate the soldiers, ruthlessly. To her dismay, she suddenly felt very weak and she suddenly fell to the temple floor. She glanced down at herself to see she had been hit a few times by the soldiers' gunshots.

"No!!" Isabelle cried out as she collapsed completely on the floor and bled out from her wounds.

Season 5

Thirst

Clark and Chloe began to see a different Lana ever since she joined a sorority at Met U. Wondering what caused the change from her normal self, they took it upon themselves to find out what caused this transformation.

They started their investigation by looking into the history of Lana's sorority. Chloe learned that the girl currently in charge, Buffy, took over the sorority six years ago and made it a success but would only allow one new member each year. Also, she found out that no one had left since Buffy took over. To investigate further, the pair decided to sneak into the sorority's Halloween party.

Clark searched some rooms within the sorority house and discovered an article about Buffy. The article mentioned that she survived a vampire bat attack in a Smallville cave. Before learning anything more, he was confronted by Buffy. Luck was on Clark's side when something distracted her for a brief moment that allowed Clark to super speed out of the room to avoid further questioning.

In the meantime, Chloe found Lana, who was hitting on one of the male partygoers. Chloe had to drag Lana away just to talk to her. It appeared that it wasn't the best idea when the two started fighting. Clark broke the fight between them up -- Lana left behind an injured Chloe.

With Chloe now in the hospital, it was up to Clark to figure out what was wrong with Lana. Clark's college professor, Dr. Fine, told him to talk to Lex about something called Project 1138. At the Luthor estate, Lex told him that six years ago, Buffy was trapped in a cave for several days until LuthorCorp came to her rescue. Meteor rocks were in that cave and had affected the bats. A LuthorCorp technician was afflicted but a cure was created using kryptonite.

Lex showed Clark a sample of the cure, which weakened him. Lana then came in and knocked out Lex and bit Clark.

"Lana, get off me," Clark warned her. "We can help you."

"I need no one's help, Clark. You can be one of us," Lana said as she went in for another bite of Clark's neck.

Before she could do much damage to him, he swatted her with as much force as he could muster. Fortunately, she was sent flying through a nearby window.

Lana landed roughly outside in the daylight. Exposed to the sun, she began to writhe in pain until she burned to ashes like the vampire she had become.

Splinter

Lana decided to work with Lex in trying to open an alien spacecraft that was found months earlier but was skeptical of his motives behind wanting her help. Also, she had seen Clark acting strangely ever since she received that mysterious silver rock. But Clark's behavior had not been completely out of the ordinary so she just brushed it off.

Sometime later, Lana gave Lex the rock to study to find out what it could be. Unknown to the two of them, Clark knocked out all the guards that were not far from where Lana and Lex were.

After he left Lana with the rock, Lex discovered the unconscious guards and went to investigate. To his surprise he found Clark there and they exchanged heated words. Lex tried to calm his friend but Clark's superior strength knocked Lex out to silence him for a while.

Lana overheard the scuffle and ran off. Using his super-hearing, Clark rushed off to find where Lana went. Once he found her, Clark professed to her that they belonged together.

"Lana, we're meant for each other. Can't you see that?" Clark implored.

Just like Lex had tried to do earlier, Lana attempted to settle Clark down.

"All right, Clark. Let's talk about this," Lana calmly told him.

To her chagrin, he was not doing so and believed that she was lying to him. Clark choked her until she was no longer breathing.

Professor Fine suddenly appeared. He witnessed what Clark had done but understood the reason why it happened. Fine swiftly took out an alien device to extract a long splinter from Clark only after he incapacitated him. That splinter was a piece of silver kryptonite which he would use sometime in the near future.

"Sorry, Kal-El," Fine said as he super-sped away leaving an unconscious Clark next to a very dead Lana.

Next: Seasons 6, 7 & 8