Observing the power vaccum left by Zubaz, David Cage attempts to form his own faction to seize control. He forms a pact with the dark lord Evillak, who desires the remains of Rage's essence so he can seize the Kamidogu.
Woolie leaves on vacation to fully recuperate after the shitstorm he's been through. Cage recruits The Shockmaster, Tour Guide Nixon and Hot Dog Man into his faction, the Eternal Masters Of Tactical Insertion Of Nonsense. E.M.O.T.I.O.N. assaults various superstars backstage and during matches, leading to the incapacitating injuries of Francis York Morgan, Tiger Millionaire and Gorilla Munch. York is the only one anyone cares about, leading to Cactus Pat swearing to avenge him and defeat Cage.
Pat calls in Uncenable, York's adorable tag partner and fellow former tag team champion Zach McMuscles, and Cranky. Plague is said to be too busy farming crops on his creepy RE4 farm to get involved.
In the third week, a time portal opens and a cyborg Pat from the future, known as Patron 4000, arrives to warn of Cage's true master, whose powers will convince the world that Cage is a genius game designer, funding his next project and creating the darkest timeline. He is swiftly defeated by the Shockmaster's secret electric powers. Cranky's outfit is revealed to be insulated, making him immune to the Shockmaster's powers, allowing him to defeat him. Cage begins recruiting new followers through the use of his master's dark powers.
On week four, Zach is assaulted backstage by Tour Guide Nixon, prompting Mr. McMuscles himself to explosively enter the fray, in spite of his recent skiing injury that occurred conveniently around the same time Punishment was injured. He reveals himself to have been wearing a fat suit to keep up the facade of a has-been while secretly maintaining the physique of a Greek God. He finds Nixon and destroys him with his patented Skullovania finisher. Mr. McMuscles officially joins Pat's team for the newly cemented match at the pay-per-view two days later.
Cage uses the dark arts to "convince" the board of directors of his great ideas, prompting the PPV to be rebranded as Omicon, a convention dedicated to Cage's perfect work of art. The match features Mr. McMuscles, Cactus Pat, Uncenable and Cranky against David Cage, Hot Dog Man, and Fem Baz and Kenny, both of whom have been brainwashed by Cage's black magic to believe in his cause.
The Omikron theme of love is played for the duration of the main event as Mr. McMuscles battles Cage atop the steel cage. Cage uses his master's power to copy his opponent's physique, declaring, "Nano-Emotions, son!" Their battle is as manly as JoJo.
Pat battles ferociously, destroying Hot Dog Man with ease. His comrades tell him to go on ahead while they deal with the brainwashed duo. Pat climbs the cell, mashing X as hard as he can, while a splitscreen shows the epic duel occurring at the top.
Pat joins Mr. McMuscles against Cage in the final battle. Together, the Two Best Friends stable emerges victorious when Pat tackles Cage off the cage, right through the announce table, breaking Cage in half and averting the worst timeline.
Pat is rushed to the hospital, while Mr. McMuscles works to undo Cage's dark magic. Cage is forced to suffer through Omikron himself for the first time. He complains upon being killed that "game over is a failure of game design". Upon being reminded that he designed Omikron, the shock of his hypocrisy renders Cage comatose.
Mr. McMuscles calls Woolie to ask him to return, knowing he'll need the power of El Woolio by his side to face the coming threat.