"Holmes, I need to ask you something." Watson said as Holmes experimented with the chemicals.
"What about?" Holmes asked as he carefully measured the chemicals in the test tube and mixed them together.
"What has been your worst disaster with your chemical sets?"
Just then, Holms yelped as the test tube exploded in his hands leaving burn marks up and down his arms. He turned to Watson and said, "That would be my worst mistake with my chemicals."
What would you ask Holmes?