Griffin had been talking to Kendal in the hospital corridor about Bianca's options when her sister's screams ripped through the air. Frankie, who had been coming from a different direction, raced into Bianca's room behind Griffin. They found her screaming and thrashing on the bed, a panicking Marissa by her bedside trying to hold her down.

Kendal grabbed her sister's girlfriend and pulled her away from the bed while the doctors tried to calm Bianca down. But she wasn't hearing them, she was insensible with pain. In the end Frankie had to physically restrain her to keep her still enough for Griffin to inject a sedative.

While Frankie checked on her vitals Griffin turned to Kendal, who was holding a subdued Marissa in her arms.

"I've sedated her." said Griffin. "She'll be fine for the moment."

"But what happened?" asked Kendal.

"I'm not sure." said Griffin gravely. "I know the Orpheus treatment was affecting her nerves, causing muscle pain. It would seem the side effect of David's radical new treatment is simply more pain."

"So what now?"

"I'll have to do some tests. It seems best to keep her sedated until we understand what this new injection has done to her nervous system."

"For how long?" asked Kendal the worry clear in her voice.

"I can't say." said Griffin sadly.

"Dr Castillio." called Frankie, drawing the doctor back to Bianca's bedside. "Her pulse is a little erratic."

"That could been a side effect of the treatment." said Griffin.

"Or the stress." added Frankie. "All the rest of her vitals seen strong and her reflexes are good.

"Good." said Griffin, pulling his fingers through his hair. "I think our first course of action is a scan of her spine, make sure there isn't a more obvious cause for this pain. Maybe David's injection was misaligned and caused some damage."

"Very good. I'll call down to CT." said Frankie, "And maybe…"

Frankie nodded his head in Marissa's direction. For the first time Griffin noticed the young woman was visibly shaking and it seemed Kendal's arms were the only thing holding her up.

"Marissa." said Griffin, trying to draw her away from starring at Bianca's bed. It took her a moment to register Griffin was speaking to her.

"Marissa." He said again softly.

Marissa met is eyes.

"She was screaming." Marissa stammered. "I thought she was okay and then she started screaming."

"Did she say anything, where the pain was?" Griffin asked.

"What?" asked Marissa, finding it hard to stay focused. "No… no… she just said it hurt and… and… begged for me to make it stop but I didn't know how!"

"It's okay." said Griffin calmly, leading her, with Kendal's help, to a chair. "She's sleeping now. She's not in any pain."

"But she was screaming." repeated Marissa, her mind clearly trapped in that moment. "She never screams."

"I know." said Griffin, taking Marissa's trembling hands. "Marissa, you are in shock. Do you understand? You are feeling shaky, yes, and a little sick?"

Marissa nodded.

"I think it best if we take you somewhere you can have a lie down."

"I can't leave her." sobbed Marissa. "I won't."

"We are about to take Bianca down for some tests to try and find out what has happened. We might be some time."

"I'll stay with you." said Kendal, putting her hand on Marissa shoulder. "We can wait together."

Marissa turned her head towards Kendal as if registering her for the first time.

"I don't think I could sleep."

"You don't have to sleep. You just have to rest." insisted Kendal starring back at Griffin for support.

"That's right." said Griffin. "And I'll let you know about Bianca as soon as I find something, okay."

"Okay." said Marissa in a quiet voice, her eyes drawn once more to Bianca, sleeping peacefully in her bed. "She's going to be alright."

"Marissa…" began Griffin, but Marissa wouldn't hear it.

"No." she insisted. "She is going to be alright!"