When a dormant Mass Effect is activated by Battarian pirates, it is affected by a mysterious phenomenon that displaces the Dreikruz en route to their final confrontation with the Quaestors. Now stranded Mitsuba and the Dreikruz have to put differences aside in order to work together with the Normandy SR-2 against the Collectors and the following Reaper war. For better or worse.

In one universe, the Systems Alliance and humanity as a whole were seen as unprofessional and incompetent. In an another universe, it became a different story when humanity's early stages in space were wrought in blood, sweat, and tears. Mass Effect is owned and created by Bioware while the Super Robot Wars is owned by Bandai and other respected creators of the series included.

During the Battle of the Citadel, the Council should have been lost. The sudden arrival of three mysterious strangers changed that, and many more events yet to come.