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Wanting to get the Book of the Damned back, Monroe Styne sends his son, Eldon, to track down Sam and Dean to find it. Eldon and another family member ambush Dean, but he manages to kill the other family member and capture Eldon. Eldon explains to Dean that the Styne family has existed for thousands of years, and they harvest organs to transplant into themselves to make them superhuman. The Stynes cause, and take advantage of, various disasters in history to make a profit includingAdolf Hitler's rise to power and theSeptember 11 attacks. The family is worldwide and was formerly known by the name of Frankenstein beforeMary Shelleydiscovered their secrets and wrote a book about it. Dean goes to confront Sam after Eldon reveals that the Book of the Damned can't be destroyed. Eldon escapes by ripping off his own arm. At the same time, Crowley searches for his missing mother with help from Olivette. Sam, Rowena, Castiel, and Charlie work on decoding the Book. After having too much of Rowena, Charlie leaves to have peace and quiet, and ends up in a motel. However, right as she finally breaks the code, she gets attacked by Eldon. Sam and Dean, who has finally learned the truth, tell Charlie to give Eldon what he wants, but she destroys her computer instead of letting Eldon get her notes. Shortly afterwards, Sam and Dean find her dead, murdered by Eldon. However, as her last act, Charlie emailed them her notes on how to break the code so they could finish her work.
back at the bunker castiel and bella made love again