Onto what would be the last arc of series two of this story! Unfortunately, I could not find an appropriate enough comic title to label it as, so I'll simply call it: Away from Home!

…It's a title belonging to a Spider-Man related piece of media. It'll do.

Soon enough, Peter and his friends would be taken by All Might to I-Island as a reward for completing their entrance exams, as well as giving himself a chance to meet up with his friend David Shield and his daughter Melissa. Peter begins to talk to David, finding him interesting to listen to as he spoke about how the solutions to many of mankind's genetic diseases and problems could be from the animal kingdom itself.

However, during their conversation, Peter would notice a vial of green blood on David's desk, and with a little bit of prodding, would answer that it was a vial of blood recovered from a battle months ago, against a villain from the USJ attack. David had been sent the sample to experiment with, and had seen how it had augmented the person that had used it, and had combined it with lizard DNA to see if it could solve the problem of limb replacement, but so far all his experiments have come up with failures. Peter quickly realises that this is the Green Goblin's blood, and is barely comforted by the fact that David hasn't experimented on any living things, of which he refutes on moral and ethical concerns.

But then the island is attacked by Wolfram and his villains, having been tipped off to a powerful device being monitored at I-Island by Samuel, David's partner. Spider-Man and his friends try to intervene, but the villains lock down the island, and confront Connors about the project, as he had been working on it as well. When David at first denies the project's existence, and then refuses to allow them to have it, Wolfram, in a rage, injects the rejected hybrid blood into Connors, intent on letting him die slowly from it.

Instead, David is mutated by the blood, and transforms into a monstrous, mindless creature known as the Lizard.

The Lizard soon goes on a rampage, forcing Spider-Man to go after him to try and contain him. In the scientist's lab, Momo, Melissa, and the others try to manufacture a cure for David's condition, but find that they are unable to and have to focus on Wolfram and his goons as they run amuck through the artificial island.

Meanwhile, Peter goes up against the Lizard, but is unable to talk the now mindless and mutated David down, and is forced to try and incapacitate the raging monster. However, the Lizard is too strong for him to take down, and he is forced to retreat as the Lizard continues its rampage.

Wolfram, meanwhile, Samuel about their project, and Samuel, under hopes of receiving a massive payment for his efforts, leads him to the project in question, a major source of power that they had been using to power the entire island in lieu of any generators.

The Power Stone.

Wolfram then kills Samuel, and takes the stone for himself, leaving I-Island without any power as it begins to sink into the ocean.

With the power out across the island, All Might is freed from his confines, and he meets up with Spider-Man to both defeat the Lizard, driving it back and forcing it into the water. Realising that Wolfram is the bigger threat, both All Might and Spider-Man are forced to leave the Lizard for now, and head off to chase after the terrorist…

Who has just finished executing the rest of his cohorts, no longer needing them, and having been driven mad by the Power Stone's unlimited, well, power.

With Momo and the others, they figure out that the island has backup generators, and move to activate them before I-Island sinks into the sea, drowning everyone aboard. Fighting their way through the rogue security bots in their way, Momo and Melissa are able to restore power to the backup generators, refloating I-Island once more and saving everyone's lives. With that done, they move to join Peter and All Might at the top of the island.

Up above, Spider-Man and All Might find themselves unable to defeat Wolfram, the villain too juiced up on the Power Stone and throwing too many attacks at them to be beaten by conventional means. Each attack that they throw at the villain is blocked and countered with an overwhelming riposte. Nothing that they do is working.

But then, they get word from Momo and Melissa, and they suggest using the backup generators to feed excess power into him. So much that he will overheat from the power and burn up. Peter is against this plan, as it would mean killing Wolfram, which is not something that he nor his friends are willing to do, but All Might tells all of them that there is no other way, and they are forced to accept that.

So, All Might and Peter keep the power-drunken Wolfram's attention on them, keeping him distracted and allowing Momo and the others to push electricity into Wolfram, overloading the Power Stone, and flooding him with energy…

Eventually, Wolfram is unable to contain and control the power of the Infinity Stone in his possession, and he overloads, releasing his grip on the Power Stone, but resulting in being rendered catatonic, functionally braindead now thanks to the stone. Peter and the others are upset at this outcome, especially with all the other deaths today, even if all of them are on the villain's side, the fact that no innocent people were killed and the island was saved is able to sooth them over.

However, that salve is worsened when they find the Lizard, the mutated David Shield, escaping from the artificial island and swimming away to parts unknown…

In the aftermath of the battle, I-Island is left to rebuild, but Melissa is inconsolable at the loss of her father and his mutation into a monster, on top of the betrayal and death of someone that she saw as an uncle. Peter, Izuku, All Might, and the others would attempt to console her, but she would request time to be on her own, needing space to process everything that has happened to her.

Then, All Might confronts Peter, and reveals that he knows that Peter has something to do with the stones that Green Goblin used in his glove, as well as the one that Wolfram was using as well. Peter is forced to reveal that the stones are a source of power, and he's been desperately trying to recover them in order to seal them away and make sure that no one could use them for their own sinister purposes, like Goblin and Wolfram were. All Might is hesitant to believe this, suspicious and obvious to the fact that Peter is still hiding things from him and the others, but remembers all the good that he's done already, with Sandman and the USJ, whatever was happening with Todoroki, Hosu, and now I-Island, and decides to take his word on it.

Peter then raises the question of why David and Samuel had the Power Stone and Green Goblin's blood, and, after looking over I-Island's computer files, find that there is nothing on the systems that give them any answers, nor any paperwork that they can find. David, Samuel, and Wolfram were the only ones who knew about the Power Stone, and now with Samuel dead, Wolfram comatose, and their minions all deceased, the only one with the answers that they needed was David, and he was a mutant lizard monsters now, gone go who knows where. If they truly wanted answers to their questions, they would need to find and cure him as soon as possible.

Soon enough, once I-Island is repaired and operational once more, and once all the civilians inside are safe and sound as well, Peter and the others would leave the island and head back for the mainland, the Power Stone in their possession and their bonds still strong thanks to their combined efforts in both defeating the villains and saving the innocent, though somewhat strained now due to the fact that Peter was hiding things from them now becoming clear…

…And meanwhile, the Lizard is caught by a pair of heroes and administered a temporary cure to him, telling the suddenly lucid, but still half-mutated David, that he was coming with them. His work was to be continued…

Originally, I was going to have Curt Connors appear to be the Lizard once again, but then I figured that that was a wasted opportunity and much too predictable. So instead, I saw that David Shield was here, and figured, "Hey, there's a well-intentioned scientist who made some seriously screwed-up decisions in the heat of the moment, he'll do!" and voila, we have a new origin for the Lizard!

(I've got two versions of how he would look in my head. I feel like the first stage of David's mutation into the Lizard would look like something out of The Amazing Spider-Man film, with all the uncanniness that comes with it (seriously, look at that thing. It looks way too human for my tastes), whereas the second stage would make him into something akin to how the Lizard looked in the Marvel's Spider-Man 2 game that came out recently.)

You know, I hadn't been expecting to have this much fun out of playing with both the Spider-Man mythos and the My Hero Academia universe this much. Originally it was just going to be a case of 'One character gets plopped into another, oppsies, now go from there', but now I'm really starting to combine and meld elements of both properties together, which is always fun for me. It keeps the readers and myself on our toes, and it makes it fun to see what my readers can get out of these mergers of canon characters and ideas, and try to guess what is going to happen next. It's always fun to keep your audience second guessing. It's as much fun for me as it is for you!

Also, while I knew that I really wanted the Lizard to be one of the main antagonists of this arc, I didn't want him to be its big bad either. That role belongs to Wolfram. The reason for this is because I wanted to give the MHA villains some respect and credence. So far they've more or less been overshadowed by the Sinister Six and Spider-Man's other villains, and I wanted to make it clear that the villains of MHA are still very much a threat and are still incredibly dangerous, and I felt that making what MHA's fandom considers to be a second-rate and rather inconsequential and flat villain such as Wolfram over some of the more well-known villains would help in doing this.

(I just realised that since Wolfram has a magnetism quirk, or at least the ability to manipulate metal, I could've made it so that he was Magneto's cousin or something. Dammit, missed opportunity.)

But anyway, that's series two of this story down.

Now series three? Now that's where we really begin to get into the meat of this story!