Madeleine Stein: Has been chosen by the school's upper queens to be the Queen of the Sixth Grade. This sudden realization means Madeleine, who once feared being friendless, will now be the most popular girl in school. However, Madeleine must now question whether she has the necessary skills and poise to effectively rule over an entire grade.

Scarlett Wilson: Has been friends with Madeleine Stein since fifth grade, and she now realizes that Madeleine wants to climb the social ladder at Prescott Preparatory School for Girls. Determined to help her best friend, Scarlett instigates herself as Madeleine's second-in-command. However, Scarlett must now keep the school's social outcasts from trying to become part of Madeleine's elite social circle.

Kayla Adams: Craves popularity and acceptance among the mean girls at her new school. Determined to secure a spot in the inner circle led by Madeleine, the queen bee, Kayla believes aligning herself with this influential clique is the key to achieving her social aspirations. However, Kayla's path to securing her place in Madeleine's court remains uncertain.

Mackenzie Frost: Joining Madeleine's court offers Mackenzie a chance at popularity, and she is more than capable of handling any challenges that arise. However, Mackenzie's tendency to gossip may either aid or hinder her cause - will it help her gain favor, or will it further alienate people and erode their trust in her?

Audrey Webster: Audrey, known as Addie, is pleased that her parents transferred her to private school. Now, she must secure a place in Madeleine's inner circle. Can Addie help Madeleine maintain the spotlight on the Beauty Queens?