Claire & Leon came back from fighting Barbas. They meet up with Chris & Jill,who had been worried sick since after their disappearance. He reveals that Sherry Birkin is in state custody after the death of her parents. They are being sent out to look for an escaped fugitive,Billy Coen,a former soldier who supposed to sent to be executed.
They are joined Barry Burton & Rebecca Chambers. They notice a train for Umbrella employees in the woods. As they investigate,They are attacked by Zombie. They are saved by Billy & another escaped prisoner,Steve Burnside. They took them to their hideout where Billy reveals that he was falsely arrested for not killing unarmed villagers. He tells them that the Umbrella Corporation are carrying Vials of T-Viruses & Veronica Viruses and sells some to some Arms Dealer.
They received two signals going on. One is in the warehouse & the other is in the Island. They went to the warehouse first where they discovered a hidden lab. They are soon confronted by Albert Wesker,who survived the gunshot. He reveals that he working with Umbrella Corporation & shows them the Tyrant Project. It broke out & pursues them. Steve holds off the Tyrant before being killed,allowing them to escape.
They soon arrived at the Island where the people who are not infected greeted them. That Morning,Claire notice a same boat the Tyrant onto during their escape. She warns the people as the Tyrant attacks. Chris & the others starts firing. Billy threw the axe at the monster,allowing Chambers to kill it with an RPG that she found in the basement. The Group received contact with other survivors. Claire & Leon knew that Wesker won't give up this seriously.