Dante was resting in his trailer when a young woman,Kat tells him that he's in danger. The Hunter demon drags him into limbo & smashes his trailer parked at the end of Bellevue Pier. Dante grabs his weapons & slays the Hunter. After Dante returns to the human world,Kat takes him to meet Kyle Ryder,who tells him that the Masked Man was hunting down Dante because he was born a Nephalem,Child of an Angel,Eva & a Demon,Sparda. Ryder tells him that the Masked Man killed his parents for the murder of his Demon King,Mundus. Dante agrees to find the Masked Man. Dante confronts the Masked Man & battles with him.
As he holds him at Sword Point,The Succubus appears & attacks Dante. She was about to kill him,but stopped by the Masked Man. Dante manage to kill her,but not before the Masked Man got his mask fall off,exposing himself as the same face as Dante's. The Man reveals himself as Vergil,twin brother of Dante,who explains that Mundus was the one who killed Sparda for his betrayal when he fell in love with Eva. Realized the truth,Dante confronts Kyle,who sheds into his Demon Form,reveals himself as Mundus & uses him to try to kill his brother. Vergil appears to help Dante face off with him. With Kat's help,The brothers kills Mundus.
With the Demon King dead,& the Hell Gate closed,Limbo has now merged with the real world & the humans now see that the demons are real. As Dante & Kat looked over the horizon,Vergil assures him that the Demon who are loyal to Mundus,will be coming for them. Dante will able to keep protecting the humans & hunt down the demons.