The year is GC 0070. Nearly three decades have passed since the arrival of the Systems Alliance shook the wider galaxy to its core. While the fires of war within the Alliance have died down, the embers still burn, many beyond the borders of Alliance Space, threatening to ignite once more. And in the background, an ancient threat begins to stir.

When a dormant Mass Effect is activated by Battarian pirates, it is affected by a mysterious phenomenon that displaces the Dreikruz en route to their final confrontation with the Quaestors. Now stranded Mitsuba and the Dreikruz have to put differences aside in order to work together with the Normandy SR-2 against the Collectors and the following Reaper war. For better or worse.

During the Battle of the Citadel, the Council should have been lost. The sudden arrival of three mysterious strangers changed that, and many more events yet to come.