Now you might wonder, what exactly happened with Hermione and Ronald, right?
Let's start as one should, ladies first.
After Harry called her a mudblood, Hermione was devastated. But as so often, she didn't find any fault in herself. Instead, she blamed the Slytherins for Harry calling her that disgusting word and she did what she did best, she complained to a teacher.
Professor McGonagall was the one who had to sit through her angry rant. When the old deputy headmistress had suffered through five minutes of "they manipulate him!" and "how dare he?" she finally spoke up.
"Miss Granger, would you mind explaining to me in detail what exactly happened?" she narrowed her eyes at the fourth-year and continued "and leave no details out"
And so, always the teacher's pet, Hermione retold everything that happened during her confrontation with Harry and his new friends.
When she finished, McGonagall sighed and fixated Hermione with a fierce glare "So just that I got it right, first you took someone else's possession, refused to give it back, then yelled at a six year old boy, insisted that the people he trusts are just using him, declared yourself his closest friend, even though you know that he doesn't remember you, and then said you are like his mother, whom he never met. Did I miss anything?"
The bushy-haired witches face flushed in embarrassment and she said "Well, when you put it like that"
The Professor pulled out a thick folder and opened it. Curiously, Hermione took a peek into it and saw that in the folder were the records of every student in her year. McGonagall stopped at her record. "Miss Granger, I will investigate this whole incident. I will question Mister Weasley, Mister Zabini, Miss Lovegood, Miss Davis, the Misses Greengrass and Mister Potter about this incident. Depending on what they will tell me, it will affect my decision of making you a prefect next year"
Hermione stared at her head of house in shock "You are seriously considering taking the word of four Slytherins as a base for something you promised me last year?"
"I never promised you that you will be made a prefect, I merely stated that you were the most likely candidate for it. And considering how you behave right now, I am honestly doubting my own words"
"But they are Slytherins! They will always lie to get a Gryffindor like me in trouble!"
"The four students in question have a pristine record and never showed any kind of bigotry, as opposed to you right now"
McGonagall then made a note on Hermione's record and asked her to leave her office.
From then on, the life of Hermione went downhill.
She never became a prefect, her behaviour during and after her confrontation with Harry was a lot but certainly not something one would expect from a prefect. The fact that Hermione only had two more or less real friends also spoke against her.
McGonagall also received a lot of complaints from other Gryffindors in the last four years that Hermione was nagging them, sometimes downright harassing them to study more, quick to anger and very anti-social.
Her marks also got worse after her O.W.L.s, because in sixth and seventh year the curriculum demanded that the students linked different fields of magic in written and practical work, the downfall for someone like Hermione, who was only good at remembering stuff.
After Hogwarts, she got a job at the Ministry where she then tried to make the wizarding world "better".
To her dismay, every law she proposed to her superiors or agenda she tried to push through got denied each time. She never tried to view it from the wizard point of view, always looking at it like a muggle.
The relationship with her parents and family died pretty much the moment she left Hogwarts. At home, Hermione would always complain that the house of her parents was unfit for her magical needs. The two dentists endured the behaviour of their daughter for two months before they kicked her out, tired of constantly getting talked down to because they couldn't do magic.
At twenty-seven, Hermione was all alone. She never found someone to date and marry, neither in the magical, nor the mundane world. Her career never bloomed into something more than a name-and faceless Ministry worker who had sixty-two cats.
Ronald Weasley left Hogwarts after his multiple honour laps in school. He only got the bare minimum of N.E.W.T.s, then he applied for numerous Quidditch teams as a keeper.
But because he had no prior experience in playing Quidditch in at least a semi-professional setting, he was always denied.
He then drifted through multiple low paying jobs until he finally got a position as the reserve keeper of the second team of the Chudley Cannons.
Opposed to Hermione, he managed to get married to Millicent Bullstrode. Their marriage wasn't out of love or even the tiniest bit of affection, it was because the two pureblood children felt that it was their job to get married at some point in life.
The pair had ten children, all boys, one dumber than the other. None of them made any kind of impactful career.
And that's what happened to Harry's former friends that turned their backs on him when he needed them.
The end